Intermediate of iodixanol and method for preparing iodixanol by using intermediate

The invention provides a method for preparing iodixanol from an intermediate of iodixanol. The intermediate of iodixanol is shown as a formula VI: 5,5'-[(2-hydroxy-1,3-propanediyl)bis(acetylimino)]bis[N,N'-bis(2,3-dihydroxypropyl)-1,3-benzenedicarboxamide], and iodination is performed through the formula VI to obtain a finished product of iodixanol. The invention provides a brand new synthesis thought of forming a dimer first and then conducting iodinating, and in the prepared iodixanol finished product, the total impurity content is less than or equal to 1.0%, and the impurity G content is less than or equal to 0.5%. The method disclosed by the invention is mild in reaction condition, low in equipment damage, simple in process, green, environment-friendly, low in cost, capable of ensuring continuous production of high-quality products, relatively high in application value and suitable for industrial production. 本发明提供了一种碘克沙醇的中间体制备碘克沙醇的方法，碘克沙醇的中间体式VI：5,5′-[(2-羟基-1,3-丙二基)双(乙酰基亚氨基)]双[N,N′-双(2,3-二羟丙基)-1,3-苯二甲酰胺]，