Method for improving growth activity of pichia pastoris through heat treatment

The invention provides a method for improving the growth activity of pichia pastoris and a fermentation method of a pichia pastoris strain. The method provided by the invention comprises the step of carrying out heat treatment on a pichia pastoris seed solution. By adopting the method provided by th...

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Bibliographische Detailangaben
Hauptverfasser: PAN SIHUI, GU SITIAN, NIU QIWEN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a method for improving the growth activity of pichia pastoris and a fermentation method of a pichia pastoris strain. The method provided by the invention comprises the step of carrying out heat treatment on a pichia pastoris seed solution. By adopting the method provided by the invention, the growth of the pichia pastoris can be obviously promoted, the growth and reproduction period of the early stage of a fermentation process of the pichia pastoris is shortened and the pichia pastoris enters an enzyme production stage more rapidly. 本发明提供了一种提高毕赤酵母生长活力的方法以及毕赤酵母菌株的发酵方法。本发明提供的方法包括热处理毕赤酵母种子液的步骤进行热处理。采用本发明的方法可明显促进毕赤酵母生长,有利于缩短毕赤酵母发酵过程前期的生长繁殖期,更快地进入产酶阶段。