Method for synthesizing polyhexamethylene biguanide from monoguanidine intermediate

The invention provides a method for synthesizing polyhexamethylene biguanide from a monoguanidine intermediate, and relates to the technical field of synthesis of polyhexamethylene biguanide compounds. The method comprises the following steps: firstly, taking dicyandiamide salt and hexanediamine or hexanediamine salt as raw materials, carrying out unilateral reaction to generate a monoguanidine intermediate, carrying out simple treatment, and conducting heating and auto-polymerization to obtain PHMB. The method not only can avoid the complicated treatment process in the traditional synthesis of the biguanide intermediate, but also can avoid the defects that the salt content of the product produced by a one-pot method is too high and is difficult to remove, the synthesis and post-treatment processes are simple, the product quality is easy to control, and the method is a simple, convenient and efficient synthesis method. 本发明提供了一种由单胍中间体合成聚六亚甲基双胍的方法，涉及聚双胍化合物合成技术领域。该方法首先以双氰胺盐和己二胺或己二胺盐为原料，进行单边反应生成单胍中间体，经简单处理后再升温自聚合