Anti-PDL1 KDR bispecific antibody

The invention provides an anti-PDL1 * KDR bispecific antibody. Experimental results show that the bispecific antibody can well maintain the activity of respective monoclonal antibodies, can be specifically bound to two target spots PD-L1 and KDR at the same time, and has good physicochemical propert...

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Bibliographische Detailangaben
Hauptverfasser:	ZHU HAIXIA, ZHU ZHENPING, HUANG HAOMIN, GU CHANGLING
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention provides an anti-PDL1 * KDR bispecific antibody. Experimental results show that the bispecific antibody can well maintain the activity of respective monoclonal antibodies, can be specifically bound to two target spots PD-L1 and KDR at the same time, and has good physicochemical properties. 本发明提供了一种抗PDL1×KDR的双特异性抗体，实验结果显示该双抗能够较好的保持各自单抗的活性，并且能够同时特异性结合PD-L1和KDR两个靶点，具有良好的理化性质。