NOVEL OXALYL PIPERAZINES ACTIVE AGAINST THE HEPATITIS B VIRUS (HBV)

The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: DONALD ALASTAIR, RAYMOND JUSTINE, GOLDNER THOMAS, BONSMANN SUSANNE, URBAN ANDREAS, BARRIOS ESTHER ALZA, PERICÀS BRONDO MIQUEL ÀNGEL, DETTA ELENA
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The present invention relates generally to novel antiviral agents. Specifically, the present invention relates to compounds which can inhibit the protein(s) encoded by hepatitis B virus (HBV) or interfere with the function of the HBV replication cycle, compositions comprising such compounds, methods for inhibiting HBV viral replication, methods for treating or preventing HBV infection, and processes and intermediates for making the compounds. 本发明总体上涉及新型抗病毒剂。具体来说,本发明涉及可以抑制由乙型肝炎病毒(HBV)编码的蛋白质或干扰HBV复制周期的功能的化合物,包含此类化合物的组合物,抑制HBV病毒复制的方法,治疗或预防HBV感染的方法,以及制造所述化合物的方法和中间体。