Preparation method of 9-benzylidene fluorene compound

The invention discloses a novel synthesis strategy for a 9-benzylidene fluorene compound. According to the invention, a five-membered ring palladium intermediate generated in situ and an alkenyl bromide compound are subjected to oxidative addition to generate a Pd (IV) complex, and then reduction elimination and Heck coupling are carried out to generate the 9-benzylidene fluorene compound. The synthesis strategy has the advantages of simple reaction operation, high target product yield and high atom economy. 本发明公开了一种9-苄亚甲基芴类化合物的合成新策略，利用原位生成的五元环钯中间体与烯基溴类化合物进行氧化加成生成Pd(IV)配合物，然后还原消除和Heck偶联生成9-苄亚甲基芴类化合物，该合成策略具有反应操作简单、目标产物收率高，原子经济性高的优点。