Acellular matrix fiber and preparation method thereof

The invention relates to an acellular matrix fiber preparation method thereof, which comprises the steps of: S1, taking a wet acellular matrix, cutting the acellular matrix into fragments, and carrying out high-speed mashing in a short time; S2, mixing the acellular matrix, glacial acetic acid and p...

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Hauptverfasser: PAN YINGEN, CHEN JIANZHONG, WU FENG, PAN HUAQIAN
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention relates to an acellular matrix fiber preparation method thereof, which comprises the steps of: S1, taking a wet acellular matrix, cutting the acellular matrix into fragments, and carrying out high-speed mashing in a short time; S2, mixing the acellular matrix, glacial acetic acid and purified water, and cooling; and S3, homogenizing at a certain frequency, collecting feed liquid, circulating for a plurality of times, filtering out coarse particles, adjusting the pH value of the filtered slurry by adopting a NaOH solution, and centrifuging to obtain the acellular matrix fiber. According to the preparation method, fibrosis is performed on an acellular matrix, and the acellular matrix is homogenized; and by controlling the process conditions, the degeneration degree of the acellular matrix fibers can be improved, so that the microcosmic local surface degradation performance is improved, and vascularization is promoted. 本发明涉及一种脱细胞基质纤维的制备方法,步骤包括:S1、取湿态的脱细胞基质,将其剪成碎片后,在短时间内进行高速捣碎;S2、取所述脱细胞基质、冰醋酸以及纯化水,混