Drug-coated balloon

Described here are devices, systems, and methods for treating conditions or diseases of the nose, ear, or throat with an expandable device having a drug coating. The expandable devices may be delivered to a body cavity in a low-profile configuration and expanded to contact surrounding tissue. The expandable devices may deliver or release the drug coating to the tissue. Multiple expansions of a single device may be employed during treatment. Various coating excipients and manufacturing parameters for the expandable devices may also be adjusted to enhance or slow transfer of the drug coating and/or release of the drug to the target tissue site. The drug transferred to the tissue may act as an in situ depot that enables maintenance of a therapeutic level of locally delivered drug for a desired time period after removal of the expandable devices. 本文描述了用具有药物涂层的可扩张装置来治疗鼻、耳或咽喉病症或疾病的装置、系统和方法。可扩张装置可以以隐蔽性构造递送到体腔，并且被扩张以接触周围组织。可扩张装置可以将药物涂层递送或释放到组织。在治疗期间可以使用单一装置的多次膨胀。还可以调节用于可扩张装置的各种涂层赋形剂和制造参数，以增强或减慢药物涂层的转移和/或将药物释放到靶组织部位。转