Chicken infectious laryngotracheitis recombinant virus strain and application thereof

The invention provides a chicken infectious laryngotracheitis recombinant virus strain and application thereof. The chicken infectious laryngotracheitis recombinant virus strain is obtained by deleting an ORFC gene of a chicken infectious laryngotracheitis virulent strain, and screening after homolo...

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Bibliographische Detailangaben
Hauptverfasser:	YU XIAOLU, FAN GENCHENG, GUO WEIWEI, HOU YUCHAO, LI ZHEN, SUN HUALU, CHU DIANFENG, DU YUANZHAO, SUN PENG
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention provides a chicken infectious laryngotracheitis recombinant virus strain and application thereof. The chicken infectious laryngotracheitis recombinant virus strain is obtained by deleting an ORFC gene of a chicken infectious laryngotracheitis virulent strain, and screening after homologous recombination rescue. The preservation number of one specific infectious laryngotracheitis recombinant virus is CCTCC NO: C202158. The infectious laryngotracheitis recombinant virus provided by the invention is used for preparing vaccines. The virulence of the ILTV gene-deleted attenuated strain provided by the invention is obviously weaker than that of a parent strain, the side reaction caused after immunization is obviously smaller than that of the existing vaccine strain K317, and the ILTV gene-deleted attenuated strain can provide a good protection effect on the current epidemic ILTV. 本发明提供一种鸡传染性喉气管炎重组病毒株及其应用，所提供的鸡传染性喉气管炎重组病毒株是将鸡传染性喉气管炎强毒株的ORFC基因进行缺失，通过同源重组拯救后筛选获得的。其中一种具体的传染性喉气管炎重组病毒，其保藏号为CCTCC NO：C202158。