Pharmaceutical composition containing ambroxol hydrochloride and preparation method of pharmaceutical composition

The invention provides a pharmaceutical composition containing ambroxol hydrochloride and a preparation method of the pharmaceutical composition. The pharmaceutical composition comprises the ambroxol hydrochloride, a sweetening agent, a pH regulator, an aromatic and a solvent, and does not comprise...

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Hauptverfasser: ZHANG WANYU, LIU DONG, WANG LIANDI, XIE YA, GAO WANFENG, LI RUILAN, LIU FANG, ZHANG JIANLI, XIE YUHONG, SU XIAOFENG, FANG XIANLUO
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention provides a pharmaceutical composition containing ambroxol hydrochloride and a preparation method of the pharmaceutical composition. The pharmaceutical composition comprises the ambroxol hydrochloride, a sweetening agent, a pH regulator, an aromatic and a solvent, and does not comprise a thickening agent and a preservative; and the pharmaceutical composition does not contain a plasticizer and the preservative, is excellent in drug stability, and can reduce or avoid allergic reactions, reduce carcinogenicity and improve drug safety. Besides, by removing the thickening agent, the relative density of the pharmaceutical composition can be effectively reduced, the retention time of the drug in the oral cavity when a patient takes the drug is shortened, the compliance of the patient is improved, the taste is better, the industrial production filtering efficiency is improved, and accurate filling is achieved. In addition, the pharmaceutical composition disclosed by the invention adopts single-dose filli