ANTI-HER2 ANTIBODY-PYRROLOBENZODIAZEPINE DERIVATIVE CONJUGATE

A novel anti-HER2 antibody-pyrrolobenzodiazepine (PBD) derivative conjugate; a medicine using the antibody-drug conjugate that has a therapeutic effect on a tumor; and a method for treating a tumor using the antibody-drug conjugate or the medicine. 本发明涉及一种新型抗HER2抗体－吡咯并苯并二氮杂卓(PBD)衍生物偶联物、使用了该抗体－药物偶联物的...

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Hauptverfasser:	YONEDA KOZO, HAYAKAWA ICHIRO, HARATA NAOYA
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	A novel anti-HER2 antibody-pyrrolobenzodiazepine (PBD) derivative conjugate; a medicine using the antibody-drug conjugate that has a therapeutic effect on a tumor; and a method for treating a tumor using the antibody-drug conjugate or the medicine. 本发明涉及一种新型抗HER2抗体－吡咯并苯并二氮杂卓(PBD)衍生物偶联物、使用了该抗体－药物偶联物的对于肿瘤具有治疗效果的医药品、以及使用了该抗体－药物偶联物或医药品的肿瘤的治疗方法。