Application of fucoidan in cell model construction

The invention provides application of fucoidan in cell model construction, and belongs to the technical field of drug research and development and cell model construction. According to the invention, research accidentally finds that fucoidan can obviously shorten a construction time of Caco-2 cell monolayer model, a model construction process is safe and environment-friendly, a microvillus structure grows on a surface of the constructed Caco-2 cell monolayer, and the Caco-2 cell monolayer has similar functions to small intestine epithelial cells and can be used for drug absorption and transport research. When a Caco-2 cell monolayer model needs to be established in scientific research or experiments, a method provided by the invention can be used for modeling. According to the invention, fucoidan from different sources are researched, the fucoidan capable of promoting establishment of a Caco-2 cell monolayer model is screened out, application way of fucoidan is widened, theoretical and experimental base is pr