Synthesis method and intermediate of anti-tumor compound
The invention relates to a synthesis method and an intermediate of an anti-tumor compound. The invention belongs to the technical field of medicines, and particularly relates to a synthesis method and an intermediate of an anti-tumor compound. The synthesis method disclosed by the invention has the...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention relates to a synthesis method and an intermediate of an anti-tumor compound. The invention belongs to the technical field of medicines, and particularly relates to a synthesis method and an intermediate of an anti-tumor compound. The synthesis method disclosed by the invention has the advantages that the operability is enhanced, the process is simplified, the synthesized target compound can obtain higher purity without a complicated recrystallization process, the generation of three wastes is reduced, and the synthesis method is more suitable for industrial mass production. The intermediate provided by the invention is used for preparing an anti-tumor compound. By-products in the reaction process are effectively reduced, and the total yield of the reaction is increased by at least one time compared with that of an existing synthesis method.
抗肿瘤化合物的合成方法及其中间体。本发明属于医药技术领域,具体涉及一种抗肿瘤化合物的合成方法及其中间体。本发明的合成方法可操作性增强,简化了工艺,合成的目标化合物无需再进行复杂的重结晶工艺,即可获得更高的纯度,减少了三废的产生,更适合工业化大生产。本发明提供的中间体用于制备抗肿瘤化合物,有效的减少反应过程中的副产 |
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