METHOD FOR PRODUCING PEPTIDE COMPOUND

The present invention provides a method for producing a peptide containing an N-alkyl amino acid, the method comprising the following steps (1) to (3). Step (1): Mix an N-terminus protected amino acid or an N-terminus protected peptide with a carboxylic acid halide or a halogenated alkyl formate; step (2): mix an amino acid or peptide, in which the N-terminus and C-terminus are not protected, with a trialkyl silylating agent; and step (3): mix the product obtained in step (1) with the product obtained in step (2). 本发明提供含有N-烷基氨基酸的肽的制造方法,其包括下述工序(1)至(3)。工序(1)：将N末端保护氨基酸或N末端保护肽与羧酸卤化物或卤代甲酸烷基酯混合的工序；工序(2)：将N末端及C末端未保护的氨基酸或肽与三烷基甲硅烷基化剂混合的工序；及将工序(1)中得到的产物与工序(2)中得到的产物混合的工序。