Raman spectrum detection method of phenylalanine enantiomer

The invention discloses a Raman spectrum detection method for phenylalanine enantiomers, and belongs to the field of spectral analysis and chiral recognition. The detection method comprises the following steps: taking a gold-silver nano composite material as a surface enhanced Raman scattering subst...

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Hauptverfasser: LIU XINLING, HE YANXIU, YANG HAIFENG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a Raman spectrum detection method for phenylalanine enantiomers, and belongs to the field of spectral analysis and chiral recognition. The detection method comprises the following steps: taking a gold-silver nano composite material as a surface enhanced Raman scattering substrate, taking chiral sertraline hydrochloride as a chiral selective Raman signal amplifier, adsorbing phenylalanine on the surface of the substrate, and performing chiral selective interaction with the chiral sertraline hydrochloride on the surface of the gold-silver nano composite material, and then, measuring Raman scattering signals of phenylalanine, wherein the Raman scattering signals with the high enhancement multiple are D-phenylalanine, and otherwise, the Raman scattering signals are L-phenylalanine. The Raman scattering signal of phenylalanine is enhanced through interaction between chiral molecules, detection and distinguishing of phenylalanine enantiomers are achieved according to Raman spectrum differenc