Method for preparing alpha-deoxycytidine by using strongly basic anion exchange resin

The invention discloses a method for preparing alpha-deoxycytidine by using strongly basic anion exchange resin, and belongs to the field of biological materials. The preparation method comprises the following steps: converting beta-deoxycytidine from a beta configuration to an alpha configuration b...

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Bibliographische Detailangaben
Hauptverfasser:	HUANG CHENG, MAO ZHONGHUA, QIU HONGJIAN
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOIDCHEMISTRY CHEMISTRY DERIVATIVES THEREOF METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PERFORMING OPERATIONS PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL SUGARS THEIR RELEVANT APPARATUS TRANSPORTING
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Beschreibung
Zusammenfassung:	The invention discloses a method for preparing alpha-deoxycytidine by using strongly basic anion exchange resin, and belongs to the field of biological materials. The preparation method comprises the following steps: converting beta-deoxycytidine from a beta configuration to an alpha configuration by using an alkaline reagent as a catalyst. The preparation method is simple, and a complex synthesis process can be avoided. 一种利用强碱性阴离子交换树脂制备α-脱氧胞苷的方法，属于生物材料领域。制备方法包括：利用碱性试剂为催化剂，使β-脱氧胞苷进行由β构型至α构型的构型转变。该制备方法简单，可以避免复杂的合成过程。