Preparation method of sterile amoxicillin

The invention provides a preparation method of sterile amoxicillin. The preparation method of the sterile amoxicillin provided by the invention comprises the following steps: putting amoxicillin into water to prepare an amoxicillin suspension; then acidizing and dissolving the amoxicillin suspension with hydrochloric acid at the pH value of 0.5-1.5 to obtain amoxicillin acidizing fluid; then carrying out sterilization filtration on the amoxicillin acidizing fluid by adopting a sterilization filtration filter element, and simultaneously carrying out sterilization filtration on the alkali liquor by adopting the sterilization filtration filter element; and adding the sterilized and filtered alkali liquor into the sterilized and filtered amoxicillin acidizing fluid, adjusting the pH value of the amoxicillin acidizing fluid to an isoelectric point for crystallization, and controlling the pH at the crystallization end point to be 4.5-6.0. The sterile amoxicillin prepared by the method provided by the invention has