Screening and classifying method of gastric cancer prognosis marker, gastric cancer prognosis marker, reagent for detecting gastric cancer prognosis and application

The invention provides a screening and classifying method of a gastric cancer prognosis marker, the gastric cancer prognosis marker, a reagent for detecting gastric cancer prognosis and application, and relates to the technical field of gastric cancer prognosis. The screening and classifying method...

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Hauptverfasser: LI GUOXIN, ZHENG BOYANG, ZHANG GUOFAN, LEI XUETAO, WANG HAO, YE GENGTAI
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention provides a screening and classifying method of a gastric cancer prognosis marker, the gastric cancer prognosis marker, a reagent for detecting gastric cancer prognosis and application, and relates to the technical field of gastric cancer prognosis. The screening and classifying method comprises the following steps: (1) importing information of multiple omics prognostic markers related to gastric cancer into a trained SVM model, and classifying the multiple omics prognostic markers into an A subtype, a B subtype and a C subtype; and (2) screening genes with specific expression in the A subtype, the B subtype and the C subtype to obtain the gastric cancer prognosis marker. The gastric cancer prognosis marker is related to multiple omics and survival information, the accuracy of prognosis prediction and treatment selection can be improved, and the judgment result of the gastric cancer prognosis marker is highly consistent with a real prognosis data result in TCGA. 本发明提供了一种胃癌预后标志物的筛选和分类方法、胃癌预后标志物和检测