Method for preparing intermediate N-methoxycarbonyl methyl-N-ethyl-2-methoxy-5-acetamino aniline
A method for preparing an intermediate N-methoxycarbonyl methyl-N-ethyl-2-methoxy-5-acetamido aniline comprises the step of carrying out ethylation reaction on N-methoxycarbonyl methyl-2-methoxy-5-acetamido aniline by adopting halogenated ethane in the presence of alkali and a catalyst. The method i...
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Sprache: | chi ; eng |
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Zusammenfassung: | A method for preparing an intermediate N-methoxycarbonyl methyl-N-ethyl-2-methoxy-5-acetamido aniline comprises the step of carrying out ethylation reaction on N-methoxycarbonyl methyl-2-methoxy-5-acetamido aniline by adopting halogenated ethane in the presence of alkali and a catalyst. The method is mild in condition, the yield of the intermediate N-methoxycarbonyl methyl-N-ethyl-2-methoxy-5-acetamino aniline is 92% or above, and the purity is 96% or above.
一种中间体N-甲氧碳酰甲基-N-乙基-2-甲氧基-5-乙酰氨基苯胺制备的方法,包括将N-甲氧碳酰甲基-2-甲氧基-5-乙酰氨基苯胺在碱、催化剂存在下采用卤代乙烷进行乙基化反应的步骤。该方法条件温和,并获得中间体N-甲氧碳酰甲基-N-乙基-2-甲氧基-5-乙酰氨基苯胺92%以上的收率及96%以上的纯度。 |
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