Preparation method of porous microspheres, microsphere embolization agent obtained by preparation method and application of same

The invention relates to a porous microsphere preparation method, which comprises: S1, dissolving an ethylene glycol polymer and polyvinylpyrrolidone in purified water, stirring to dissolve, adding N,N-methylene acrylamide, and adding ethyl methacrylate to dissolve so as to provide a water phase; s2...

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Hauptverfasser:	LIU CUICHAI, GUO XIAOYONG, WANG XIANG
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
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creator	LIU CUICHAI GUO XIAOYONG WANG XIANG
description	The invention relates to a porous microsphere preparation method, which comprises: S1, dissolving an ethylene glycol polymer and polyvinylpyrrolidone in purified water, stirring to dissolve, adding N,N-methylene acrylamide, and adding ethyl methacrylate to dissolve so as to provide a water phase; s2, adding liquid paraffin into petroleum ether, and adding tetramethylethylenediamine to provide an oil phase; s3, under stirring, dropwise adding the water phase into the oil phase, rapidly stirring the mixutre for 1-4 hours, heating the mixutre to 40-60 DEG C, continuously stirring the mixutre for 2-5 hours, and filtering the mixutre to obtain the porous microspheres. The invention also relates to the microsphere embolization agent obtained by the method and application thereof. According to the preparation method of the porous microspheres, the porous microspheres are obtained by dropwise adding the water phase into the oil phase. The product is of a micron-sized spherical structure with a porous structure on the
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The invention also relates to the microsphere embolization agent obtained by the method and application thereof. According to the preparation method of the porous microspheres, the porous microspheres are obtained by dropwise adding the water phase into the oil phase. The product is of a micron-sized spherical structure with a porous structure on the</description><language>chi ; eng</language><subject>CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES ; DISINFECTION, STERILISATION, OR DEODORISATION OF AIR ; HUMAN NECESSITIES ; HYGIENE ; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES ; MEDICAL OR VETERINARY SCIENCE ; METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL</subject><creationdate>2021</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20211022&DB=EPODOC&CC=CN&NR=113521378A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20211022&DB=EPODOC&CC=CN&NR=113521378A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LIU CUICHAI</creatorcontrib><creatorcontrib>GUO XIAOYONG</creatorcontrib><creatorcontrib>WANG XIANG</creatorcontrib><title>Preparation method of porous microspheres, microsphere embolization agent obtained by preparation method and application of same</title><description>The invention relates to a porous microsphere preparation method, which comprises: S1, dissolving an ethylene glycol polymer and polyvinylpyrrolidone in purified water, stirring to dissolve, adding N,N-methylene acrylamide, and adding ethyl methacrylate to dissolve so as to provide a water phase; s2, adding liquid paraffin into petroleum ether, and adding tetramethylethylenediamine to provide an oil phase; s3, under stirring, dropwise adding the water phase into the oil phase, rapidly stirring the mixutre for 1-4 hours, heating the mixutre to 40-60 DEG C, continuously stirring the mixutre for 2-5 hours, and filtering the mixutre to obtain the porous microspheres. The invention also relates to the microsphere embolization agent obtained by the method and application thereof. According to the preparation method of the porous microspheres, the porous microspheres are obtained by dropwise adding the water phase into the oil phase. 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subjects	CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL
title	Preparation method of porous microspheres, microsphere embolization agent obtained by preparation method and application of same
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