Solid state forms of oclacitinib maleate
The present invention relates to solid state forms of oclacitinib maleate and methods for the preparation of the solid state forms of oclacitinib maleate. The solid state forms of oclacitinib maleate of the present invention include amorphous oclacitinib maleate, crystalline tetramethyl urea solvate...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The present invention relates to solid state forms of oclacitinib maleate and methods for the preparation of the solid state forms of oclacitinib maleate. The solid state forms of oclacitinib maleate of the present invention include amorphous oclacitinib maleate, crystalline tetramethyl urea solvate form of oclacitinib maleate, crystalline monohydrate form of oclacitinib maleate and crystalline form of oclacitinib maleate (form B).
本发明涉及马来酸奥拉替尼的固态形式和用于制备马来酸奥拉替尼的固态形式的方法。本发明的马来酸奥拉替尼的固态形式包括无定形马来酸奥拉替尼、马来酸奥拉替尼的结晶四甲基脲溶剂化物形式、马来酸奥拉替尼的结晶一水合物形式和马来酸奥拉替尼的结晶形式(形式B)。 |
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