Application of exosome circular RNA 0109315 as target spot in prevention and treatment of benign prostatic hyperplasia

The invention belongs to the field of biotechnology and medicine, and particularly relates to application of exosome circular RNA 0109315 as a target spot in prevention and treatment of benign prostatic hyperplasia. The applicant discovers that inhibition of hsa_circ_0109315 has a certain improvemen...

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Bibliographische Detailangaben
Hauptverfasser:	LIU MIN, LIU JIANHUA, RONG NAN, CHEN JINGLOU
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES OF PREPARING SUCH COMPOSITIONS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention belongs to the field of biotechnology and medicine, and particularly relates to application of exosome circular RNA 0109315 as a target spot in prevention and treatment of benign prostatic hyperplasia. The applicant discovers that inhibition of hsa_circ_0109315 has a certain improvement effect on benign prostatic hyperplasia induced by various risk factors. The benign prostatic hyperplasia marker exosome circular RNA hsa_circ_0109315 has expression difference in peripheral blood of healthy people and peripheral blood of benign prostatic hyperplasia patients, so that the benign prostatic hyperplasia marker exosome circular RNA hsa_circ_0109315 can be used as a novel biomarker for detecting benign prostatic hyperplasia. The invention finds that the exosome hsacirc0109315 can be used as a biomarker and a drug treatment target for benign prostatic hyperplasia diagnosis for the first time, and provides a new reference index for developing a drug for preventing and treating benign prostatic hyperplasi