Olive alcohol synthase variant and engineered microorganism expressing same

The present invention provides an olive alcohol synthase variant and an engineered microorganism expressing the same for producing olive alcohol and olive alcohol acid, and more specifically, an engineered Escherichia coli, in which the engineered Escherichia coli is modified to express the olive alcohol synthase variant, the olivol synthase variant is characterized in that compared with a wild type of the olivol synthase variant, the olivol synthase variant comprises one or more of the following mutations: I303T, I52L, S56A, H262M and K263R. The engineered Escherichia coli achieves improved yields of olive alcohol and olive alcohol acid. 本发明提供了橄榄醇合成酶变体和表达其的用于生产橄榄醇和橄榄醇酸的工程化微生物，更具体地是一种工程化大肠杆菌，其中所述工程化大肠杆菌被修饰以表达橄榄醇合成酶变体，其特征在于所述橄榄醇合成酶变体与其野生型相比包含选自以下突变中的一种或多种：I303T、I52L、S56A、H262M和K263R。所述工程化大肠杆菌实现了改善的橄榄醇和橄榄醇酸收率。