Anti-diarrhea synbiotics microcapsule and preparation method thereof

The invention relates to an anti-diarrhea synbiotics microcapsule. A core material is prebiotics containing inulin nanoparticles and pediococcus acidilactici; the wall material is a pH-sensitive high-molecular compound. The invention also relates to a preparation method of the synbiotics microcapsule with pectin/chitosan as the wall material by using a nanotechnology. The anti-diarrhea synbiotics microcapsule disclosed by the invention has the advantages that the gastrointestinal tract tolerance is enhanced, the antibacterial effect is improved, the secretion amount of pediococcus acidilactici secreting pediococcus acidilactici is obviously increased by 2-3 times, and the microcapsule rapidly releases the pediococcus acidilactici loaded with inulin nano-particles in an artificial simulated intestinal environment, so that the antibacterial effect on salmonella enterica is improved. 本发明涉及一种抗腹泻合生元微胶囊，芯材为含有菊粉纳米粒子的益生元与乳酸片球菌；壁材为pH敏感性高分子化合物，同时涉及利用纳米技术制备果胶/壳聚糖为壁材的合生元微胶囊制备方法。本发明的抗腹泻合生元微胶囊对胃肠道耐受性增强、抗菌效果增加，乳酸片球菌分泌乳酸片球菌素