ORAL THIN FILMS
An orally dissolvable film includes at least one layer comprising a first pharmaceutically active ingredient; a resinate comprising an ion exchange resin and a second pharmaceutically active ingredient; and a matrix and/or binder. The provision of a first pharmaceutically active ingredient, e.g., di...
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Zusammenfassung: | An orally dissolvable film includes at least one layer comprising a first pharmaceutically active ingredient; a resinate comprising an ion exchange resin and a second pharmaceutically active ingredient; and a matrix and/or binder. The provision of a first pharmaceutically active ingredient, e.g., dispersed or dissolved in the film, and of a resinate comprising an ion exchange resin and a second pharmaceutically active ingredient, may allow immediate release of the first active ingredient, and controlled, sustained and/or delayed release of the second active ingredient.
口腔溶解膜包括至少一个层,所述口腔溶解膜包含:第一药物活性成分;包含离子交换树脂和第二药物活性成分的树脂酸盐;以及基体和/或粘合剂。提供第一药物活性成分(例如分散或溶解在膜中的第一药物活性成分)以及包含离子交换树脂和第二药物活性成分的树脂酸盐可以实现第一活性成分的立即释放,以及第二活性成分的受控释放、持续释放和/或延迟释放。 |
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