SUSTAINED-RELEASE INJECTION COMPRISING DESLORELIN, AND PREPARATION METHOD THEREFOR

The present invention relates to a sustained-release injection preparation comprising biodegradable polymer microspheres containing deslorelin as an active ingredient, and a preparation method therefor. The sustained-release microsphere injection comprising deslorelin, according to the present invention, has good administrability and enables, with a single administration, a deslorelin drug to be maintained at an effective concentration for 6 months without rapid temporary release into the blood of an animal. 本公开涉及一种缓释注射制剂及其制备方法，该制剂包含含有作为活性成分的地洛瑞林的可生物降解的聚合物微球。根据本公开的含有地洛瑞林的缓释微球注射剂具有良好的给药性，并且单次给药能够使地洛瑞林药物维持在有效浓度下6个月，而不会快速短暂地释放到动物血液中。