Pharmaceutical formulations

The invention relates to pharmaceutical formulations comprising an active pharmaceutical ingredient, a polyethylene glycol having a freezing point of at least about 30 DEG C, and a crystallisation rate inhibitor. Solid dosage forms comprising the pharmaceutical formulations, methods for preparing th...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SHAH SETUL M, HOLM RENE, KIMPE KRISTOF L, LATHUILE AUDREY A R, PROKOPCOVA HANA, NEEFS THOMAS E R
Format: Patent
Sprache:chi ; eng
Schlagworte:
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Beschreibung
Zusammenfassung:The invention relates to pharmaceutical formulations comprising an active pharmaceutical ingredient, a polyethylene glycol having a freezing point of at least about 30 DEG C, and a crystallisation rate inhibitor. Solid dosage forms comprising the pharmaceutical formulations, methods for preparing the same and use of the same in methods of treatment are also described. 本发明涉及药物配制品,所述药物配制品包含活性药物成分、具有至少约30℃的凝固点的聚乙二醇和结晶速率抑制剂。还描述了包含所述药物配制品的固体剂型、所述药物配制品的制备方法及所述药物配制品在治疗方法中的用途。