Method for preparing macrocycloalkanone from epoxide

The invention provides a method for preparing a macrocycloalkanone from an epoxide. The method comprises the following steps of: mixing a ligand L, an aluminum compound and a solvent to obtain a catalyst solution; injecting the catalyst solution and an epoxide into a reactor for reaction to obtain a reaction solution; and separating and purifying the reaction liquid to obtain the required product. Compared with the prior art, the method provided by the invention has the advantages that the reaction conditions are milder, the macrocycloalkanone can be prepared at the temperature of 50-100 DEG C, the problems of side reactions such as oxidation, isomerization and decomposition of raw materials and products and carbon deposition and coking of a catalyst caused by high-temperature reaction at 200 DEG C or above in the prior art are solved, high-selectivity and high-yield continuous preparation of the macrocycloalkanone compound is realized, generation of high-boiling-point byproducts with functional groups and si