Pharmaceutical composition containing plinabulin and application thereof

The invention relates to the technical field of cancer chemotherapy drugs, and discloses a pharmaceutical composition containing plinabulin and application thereof. The active ingredients of the pharmaceutical composition comprise plinabulin and tetrandrine. Various malignant tumor cells can be inhibited and killed through combination of tetrandrine and plinabulin, the dosage can be reduced, the treatment cycle can be shortened, toxic and side effects can be reduced, and adverse reactions caused by the toxic and side effects are reduced accordingly. A new choice is provided in the aspect of avoiding drug resistance or medicine resistance. 本发明涉及癌症化疗药物技术领域，公开了一种含普那布林的药物组合及其应用。该药物组合的活性成分包括普那布林和粉防已碱。粉防己碱和普那布林联用可抑制和杀灭各种恶性肿瘤细胞，并可以减少用药量、缩短治疗周期，减少毒副作用，由毒副作用所带来的不良反应也就随之降低。在避免抗药性或耐药性方面就又多了一种新的选择。