Disialic acid-mannan oligosaccharide compound and synthesis method thereof

The invention discloses a disialic acid-mannan oligosaccharide compound and a synthesis method thereof, and belongs to the technical field of biological medicines. According to the method, the disialic acid-mannan oligosaccharide compound is constructed by grafting oligomerization mannuronic acid with the disialic acid, and the disialic acid-mannan oligosaccharide compound has relatively good biological recognition and good antioxidant and anti-inflammatory activity, and can penetrate through a blood brain barrier and enter the brain, so that the effect of an electronegative sugar chain entering the brain and acting with A42 is improved; and meanwhile, the compound can effectively inhibit the activation state generated by BV-2 cells stimulated by A42, alleviates the damage degree and inflammatory reaction of the BV-2 cells, and is expected to be applied to prevention and treatment of Alzheimer's disease. 本发明公开了一种双唾液酸-甘露寡糖复合物及其合成方法，属于生物医药技术领域。本发明通过低聚甘露糖醛酸接枝双唾液酸构建的双唾液酸-甘露寡糖复合物，该双唾液酸-甘露寡糖复合物具有较好的生物识别性，良好的抗氧化及抗炎活