ANTI-NALOXONE AND ANTI-NALTREXONE MONOCLONAL ANTIBODIES AND METHODS OF PRODUCTION AND USE THEREOF

Antibodies that specifically bind naloxone or naltrexone are disclosed. Also disclosed are conjugates used in the production of the antibodies, as well as methods of producing the antibodies. Also disclosed are methods of using the antibodies in direct assays for naloxone or naltrexone. Further disc...

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Bibliographische Detailangaben
Hauptverfasser:	SMIRNOV YURIY, YAU HEUNGYEUNG, DOMINOWSKI ALLISON, DRAGHICI BOGDAN, TENG ZHU, MORJANA NIHMAT, ZHENG YI FENG, SHARMA MANOJ, MAREEVA TATIANA, BEDZYK WILLIAM, LEBEDEVA TATIANA
Format:	Patent
Sprache:	chi ; eng
Schlagworte:	HUMAN NECESSITIES HYGIENE INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEDICAL OR VETERINARY SCIENCE PHYSICS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES TESTING
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Beschreibung
Zusammenfassung:	Antibodies that specifically bind naloxone or naltrexone are disclosed. Also disclosed are conjugates used in the production of the antibodies, as well as methods of producing the antibodies. Also disclosed are methods of using the antibodies in direct assays for naloxone or naltrexone. Further disclosed are methods of reducing naloxone or naltrexone interference in opiate assays using the antibodies. 公开了特异性结合纳洛酮或纳曲酮的抗体。还公开了用于产生抗体的缀合物，以及产生抗体的方法。还公开了在纳洛酮或纳曲酮的直接测定中使用抗体的方法。进一步公开了使用抗体在阿片剂测定中减少纳洛酮或纳曲酮干扰的方法。