LIQUID PHARMACEUTICAL FORMULATIONS OF PTH CONJUGATES

The invention discloses a liquid pharmaceutical formulation, wherein the pharmaceutical formulation comprises a PTH conjugate, a buffering agent, an isotonicity agent, a preservative and optionally an antioxidant and wherein the PTH conjugate comprises a PTH moiety that is covalently and reversibly...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SPROGØE KENNETT, CLEEMANN FELIX, SORENSEN MICHAEL DUELUND, SKANDS ANJA R H, HOFMANN EDMONT, BALUN JOZEF
Format: Patent
Sprache:chi ; eng
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Beschreibung
Zusammenfassung:The invention discloses a liquid pharmaceutical formulation, wherein the pharmaceutical formulation comprises a PTH conjugate, a buffering agent, an isotonicity agent, a preservative and optionally an antioxidant and wherein the PTH conjugate comprises a PTH moiety that is covalently and reversibly conjugated to a water-soluble carrier moiety. 液体药物制剂,其中所述药物制剂包含PTH缀合物、缓冲剂、等渗剂、防腐剂和任选的抗氧化剂,并且其中所述PTH缀合物包含与水溶性载体部分共价和可逆地缀合的PTH部分。