Recombinant bovine nodule rash virus for expressing bovine viral diarrhea E2 gene and application of recombinant bovine nodule rash virus

The invention relates to the technical field of biology, in particular to a recombinant bovine nodule rash virus for expressing a bovine viral diarrhea E2 gene and application of the recombinant bovine nodule rash virus. The recombinant bovine nodule rash virus provided by the invention contains the bovine viral diarrhea E2 gene as shown in SEQ ID NO.1. The recombinant virus not only retains the antigen of the bovine nodule rash virus, but also expresses the bovine viral diarrhea E2 antigen, can be directly used as a live vaccine for inoculation, and does not need processes such as inactivation and adjuvant emulsification. The immunogenicity for bovine nodule rash virus and bovine viral diarrhea virus is good, bovine viral diarrhea or bovine nodule dermatosis can be prevented at the same time, vaccine immunity and wild virus infection can be differentiated and diagnosed through a commercialized differential diagnosis kit, and material guarantee is provided for epidemic disease evolution. 本发明涉及生物技术领域，尤其涉及一种表达牛