QUATERNARY AMMONIUM SALTS AS INHIBITORS OF TRIMETHYLAMINE PRODUCTION

Provided are compounds that can inhibit pathogenic, bacterial metabolite production and conjugates of the same. Also provided are pharmaceutical compositions comprising the same and methods of using the same. 提供了可抑制致病性细菌代谢物产生的化合物和其结合物。还提供了包含其的药物组合物和其使用方法。...

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Hauptverfasser: JUNG RYU, YASUDA KOJI, GUNASEKERA DINARA SHASHANKA, BOGART ELIJAH, BILLINGS GABRIEL, TEFFERA YOHANNES, DOUD DEVIN FOREST REED, BRIGGS TIMOTHY, TAYLOR STEVEN, PROUDFOOT JOHN, NUDEL KATHLEEN, AJAYI KEHINDE, MARTINEZ-DEL CAMPO ANA, PECK SPENCER C, ROSS CHELSEA, LAFRANCE DANNY
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:Provided are compounds that can inhibit pathogenic, bacterial metabolite production and conjugates of the same. Also provided are pharmaceutical compositions comprising the same and methods of using the same. 提供了可抑制致病性细菌代谢物产生的化合物和其结合物。还提供了包含其的药物组合物和其使用方法。