POLYMORPHIC FORM OF MEISOINDIGO AND MODIFIED FORMULATION OF MEISOINDIGO

The present invention relates to a novel crystal form, manufacturing procedures, pharmaceutical compositions, formulations and medicaments comprising a N-methylisoindigo crystalline, methods of preparation, and the use of the N-methylisoindigo crystalline to prepare a medicament to prevent cancer, or treat cancer or an inflammatory-related disease associated with pro-inflammatory cytokine expression and/or reduced expression of anti-inflammatory cytokines. 本发明涉及一种新型晶型、制备过程、包含N-甲基异靛晶体的药物组合物、制剂和药物、制备方法和N-甲基异靛晶体在制备用于预防癌症、或治疗癌症或与促炎性细胞因子表达和/或抗炎性细胞因子表达减少相关的炎症相关疾病的药物中的用途。