5, 6-dihydrobenzo [h] quinazoline compound and application thereof
The invention discloses a 5, 6-dihydrobenzo [h] quinazoline compound and application thereof, and belongs to the field of medicines. The 5, 6-dihydrobenzo [h] quinazoline compound as shown in the general formula I has excellent FLT3 inhibition biological activity, the FLT3 inhibition activity reache...
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Format: | Patent |
Sprache: | chi ; eng |
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Zusammenfassung: | The invention discloses a 5, 6-dihydrobenzo [h] quinazoline compound and application thereof, and belongs to the field of medicines. The 5, 6-dihydrobenzo [h] quinazoline compound as shown in the general formula I has excellent FLT3 inhibition biological activity, the FLT3 inhibition activity reaches 80% or above, the 5, 6-dihydrobenzo [h] quinazoline compound can be used as an FLT3 inhibitor, and a new way is opened up for finding a new way for treating cancers, metabolic and immune diseases, cardiovascular diseases, neurological diseases and the like.
本发明公开了一种5,6-二氢苯并[h]喹唑啉类化合物及其应用,属于医药领域。本发明通式I所示的5,6-二氢苯并[h]喹唑啉类化合物具有优异的抑制FLT3的生物活性对FLT3的抑制活性达到80%以上,可以被用作FLT3的抑制剂,为寻找新的治疗癌症、代谢与免疫疾病、心血管病以及神经性疾病等开辟新途径。 |
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