Volatile oil cyclodextrin inclusion compound and preparation method thereof

The invention discloses a volatile oil cyclodextrin inclusion compound and a preparation method thereof. The volatile oil cyclodextrin inclusion compound comprises volatile oil, cyclodextrin and an additive, and the mass ratio of the volatile oil to the cyclodextrin to the additive is 1: (8-12): (2-...

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Hauptverfasser: SUN FUREN, NIU JINWEI, GAO HAN, LIU WEI, JIN JIE, ZHANG YANYAN, LI JUNSHAN, ZHANG RUIZHI, HOU JINCAI, LIU SHA
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a volatile oil cyclodextrin inclusion compound and a preparation method thereof. The volatile oil cyclodextrin inclusion compound comprises volatile oil, cyclodextrin and an additive, and the mass ratio of the volatile oil to the cyclodextrin to the additive is 1: (8-12): (2-4); and the oil inclusion rate is 80% or above, and the additive is selected from one or more of povidone, pregelatinized starch, dextrin and lactose. According to the prepared volatile oil cyclodextrin inclusion compound, the transfer rate of volatile oil in the inclusion process is increased, the inclusion rate reaches 80% or above, and the stability of the inclusion compound is improved. 本发明公开了一种挥发油环糊精包合物及其制备方法,包括挥发油、环糊精和添加剂,挥发油、环糊精、添加剂的质量比为1:8~12:2~4;其中,油脂包合率为80%以上,添加剂选自聚维酮、预胶化淀粉、糊精和乳糖中的一种或多种。本发明制备的挥发油环糊精包合物,提高了在包合过程中挥发油的转移率,使包合率达到80%以上,提高了包合物的稳定性。