Method for estimating initial conditions of culture medium in continuous fermentation process

The invention discloses a method for estimating initial conditions of a culture medium in a continuous fermentation process, which comprises the following steps of: establishing a three-variable mathematical model of the continuous fermentation process, a linear state equation of the continuous fermentation process and a system measurement equation, and discretizing the continuous equation to obtain a discrete state space model; introducing an auxiliary variable on the basis of Kalman filtering to obtain predicted distribution obeying student distribution; representing a system state and an auxiliary variable by using a variational Bayesian theory; predicting a system state and an auxiliary variable, updating the system state and the auxiliary variable until the set number of iterations is reached, and outputting the system state and the auxiliary variable at the moment; and finishing updating until a set operation step number is reached to obtain an estimated value of the key variable in the culture medium a