Composite medicine as well as preparation method and application thereof

The invention belongs to the technical field of pharmacy, and particularly relates to a composite medicine and a preparation method and application thereof. The invention relates to a composite medicine, the composite medicine at least comprises red blood cells and artesunate, and the artesunate is entrapped in the red blood cells. Compared with the traditional artesunate injection, the composite medicine disclosed by the invention can realize slow release of the medicine after entering the body, the medicine effect can be maintained for about 9 days, the composite medicine has an obvious slow release effect, and the problems of rapid reduction of the blood concentration of the traditional artesunate injection and side effects caused by short-time multiple administration can be solved, so that malaria can be effectively prevented or treated. 本发明属于制药技术领域，具体涉及一种复合药物及其制备方法和用途。一种复合药物，所述复合药物至少包括红细胞和青蒿琥酯，所述青蒿琥酯包载于所述红细胞内部。本发明的复合药物与传统青蒿琥酯注射剂相比，进入体内后能实现药物的缓慢释放，药效维持9天左右，具有明显的缓释作用，可以解决传统青蒿琥酯注射剂的血药浓度快速下降以及短时多次给药带来的副作用问题，