Class II histocompatibility complex expression enhancing compound and preparation method and application thereof

The invention discloses a class II histocompatibility complex (MHC class II) expression enhancing compound and a preparation method and application thereof. Experiments prove that the compound has a remarkable class II histocompatibility complex expression enhancing effect, remarkable effect in enhancing class II histocompatibility complex tumor neoantigen presentation and promoting tumor tissue CD4 + T cell infiltration, and remarkable effect in inhibiting tumor growth when the compound is used independently or combined with existing immunotherapy means drugs. 本发明公开了一种Ⅱ类组织相容性复合体(MHC classⅡ)表达增强化合物、其制备方法及应用，本申请通过实验验证，所述化合物对Ⅱ类组织相容性复合体(MHC classⅡ)表达增强效果显著，对增强Ⅱ类组织相容性复合体肿瘤新生抗原呈递促进肿瘤组织CD4+T细胞侵润效果显著，单独或与现有免疫治疗手段药物联用对肿瘤生长抑制效果显著。