Construction method and application of corynebacterium engineering bacteria

The invention relates to a construction method and application of a corynebacterium engineering bacteria. According to the corynebacterium engineering bacteria disclosed by the invention, in corynebacterium host bacteria, a nucleotide sequence from -73 site to -61 site before an initiation codon GTG in the 5'-end sequence of a PC gene is replaced, and the stability of a secondary structure of the 5'-end sequence of the PC gene is reduced, so that the PC gene is easier to transcribe or express, wherein K refers to T or G. Compared with an original strain, the corynebacterium engineering bacteria have the advantages that the L-lysine synthesis efficiency is improved to a certain extent, the L-lysine yield is further improved, the production cost is reduced, the corynebacterium engineering bacteria have no conflict with an existing transformation method for high-yield L-lysine, but further verification is still needed if the corynebacterium engineering bacteria have a mutual promotion effect with the existing tr