Application of GDF15 to assessment of progress of metabolic syndrome of patient into cardiovascular disease

The invention discloses an application of GDF15 to the assessment of the progress of a metabolic syndrome of a patient into a cardiovascular disease, and particularly relates to application of a reagent for specifically determining the GDF-15 level in a sample of a subject suffering from the metabol...

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Hauptverfasser: TIAN JUNXI, HUANG CHENGYI, LONG TENGXIANG, WU TING, XU YU
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses an application of GDF15 to the assessment of the progress of a metabolic syndrome of a patient into a cardiovascular disease, and particularly relates to application of a reagent for specifically determining the GDF-15 level in a sample of a subject suffering from the metabolic syndrome in preparation of a kit for evaluating the risk of the subject suffering from the cardiovascular disease. The subject is at risk of suffering the cardiovascular disease when the GDF-15 level is increased compared to a reference amount. The application of the GDF-15 level detection kit fills up the blank of predicting the risk that the metabolic syndrome of the subject progresses into the cardiovascular disease, and the detection kit is good in accuracy, high in sensitivity, good in stability and resistant to interference. 本发明公开一种GDF15评估代谢综合征患者进展为心血管疾病的应用,具体是特异性确定患有代谢综合征的受试者的样品中GDF-15水平的试剂在制备用于在所述受试者中评估患有心血管疾病风险的试剂盒中的用途,其中,当GDF-15水平相比参照量增加时,所述受试者处于患有心血管疾病风险。该GDF-15水平检测试剂盒的应用填补了用以预测患有代谢综合征的受试者进展为心血管疾病风险的空