Antibacterial silk fibroin and preparation method thereof

The invention discloses antibacterial silk fibroin, actinomycin is loaded on the silk fibroin through a specific method, and the silk fibroin is functionalized by fully utilizing the wide biological activities of the actinomycin, such as anti-tumor, anti-bacterial, anti-virus and the like, so that the silk fibroin with high antibacterial property is prepared; the actinomycin has a good dyeing effect on the silk fibroin, the dye uptake is as high as 89.50%, and the actinomycin and the silk fibroin are firmly combined in a chemical mode, so that the prepared silk fibroin has stable antibacterial performance, and the silk fibroin combined with the actinomycin has an obvious inhibiting effect on staphylococcus aureus. 本发明公开了一种抗菌丝素蛋白，通过特定的方法将放线菌素负载到丝素蛋白上，充分利用放线菌素所具有的抗肿瘤、抗菌、抗病毒等广泛的生物活性，使得丝素蛋白功能化，制备出一种具备高抗菌性的丝素蛋白；放线菌素对丝素蛋白具有很好的染色效果，上染率高达89.50％，俩者通过化学方式牢固结合，使得制备的丝素蛋白具有稳定的抑菌性能，结合放线菌素的丝素蛋白对金黄色葡萄球菌具有明显的抑制作用。