Dispersible carbonnanohorn/gold particle nanocomposite as well as preparation and application thereof

The invention belongs to the technical field of carbon-based composite materials, and particularly relates to a dispersible carbonnanohorn/gold particle nanocomposite and preparation and application thereof. According to the preparation method, carbonnanohorn is used as a substrate, polyglycidol is...

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Hauptverfasser: ZHAO LI, LI DAOCHANG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention belongs to the technical field of carbon-based composite materials, and particularly relates to a dispersible carbonnanohorn/gold particle nanocomposite and preparation and application thereof. According to the preparation method, carbonnanohorn is used as a substrate, polyglycidol is made incovalent linkage with the carbonnanohorn and the surface of the carbonnanohorn is modified with gold nanoparticles. According to the invention, through covalent linkage between CNH and PG, a problem of dispersibility of carbonnanohorn in biomedicine is solved, and multi-aspect application of the CNH is greatly promoted; a dispersable CNH-PG-Au nanocomposite is prepared after the surface of thecarbonnanohorn is modified with the gold nanoparticles, the nanocarrier integrates functions of drug delivery and biological imaging, chemotherapy drugs are loaded, a radiotherapy sensitization effect of the Au nanoparticles is combined, and an excellent effect of the synergistic effect of chemoradiotherapy in tumor tre