Organ-like combination related to kidney cancer and application thereof

The invention belongs to the field of medicine, and discloses a kidney cancer related organoid combination and application thereof. The kidney cancer related organoid combination comprises grouping establishment of kidney cancer related organoid, selection of screening drugs and establishment of a drug sensitivity endpoint, wherein the kidney cancer related organoid is from the body of a kidney cancer patient and is selected from perirenal cells, kidney cancer cells and kidney cancer embolus tissue; and then culture is carried out in a culture medium to obtain 2D and 3D models of three organs, and drug sensitivity screening is carried out to determine drug sensitivity characteristics of patients with different kidney cancer constitutions according to establishment of a drug sensitivity end point. The inventionprovides a screening model for determining medication preference for clinical medication. 本发明属于医药领域，公开了一种肾癌相关类器官组合及其应用，包括肾癌相关类器官的分组建立、筛选药物的选择、药物敏感性终点的确立，其中所述肾癌相关类器官来自肾癌患者体内，分别选自肾旁细胞、肾癌细胞以及肾癌癌栓组织，分别经过培养基的