BEE VENOM-PURIFYING METHOD COMPRISING VIRAL CLEARANCE PROCESS AND COMPOSITION FOR PREVENTING OR TREATING INFLAMMATORY DISEASE BY USING SAME

The present invention relates to a bee venom-purifying method comprising a virus clearance process and a composition for preventing or treating inflammatory disease by using same, the method comprising the steps: (a) preparing a bee venom solution containing bee venom; (b) adjusting the pH of the bee venom solution prepared in step (a) into 2.0 to 4.0 by acid treatment to primarily deactivate viruses; and (c) filtering the pH-adjusted bee venom solution of step (b) through a nanofilter of 10-20 nm to secondarily remove viruses. 本发明涉及包括病毒清除工序的蜂毒提纯方法以及利用其的用于预防或治疗炎症性疾病的组合物，上述蜂毒提纯方法包括：步骤(a)，制备包含蜂毒的蜂毒液；步骤(b)，通过酸处理将在上述步骤(a)中制备的蜂毒液的pH值调节为2.0至4.0，来第一次灭活病毒；以及步骤(c)，通过10nm至20nm的纳米过滤器过滤在上述步骤(b)中调节pH值的蜂毒液，来第二次去除病毒。