Preparation method of 2-amino-2-(1-methyl-4-piperidyl)ethanol

The invention discloses a preparation method of 2-amino-2-(1-methyl-4-piperidyl) ethanol. The preparation method comprises the following steps: reacting 2-methyl-2-propyl-4-(1-amino-2-methoxy-2-oxoethyl)-1-piperidinecarboxylate (a compound II) with benzyl bromide under the action of an alkali 1 to generate a compound III; dissolving the compound III in an organic solvent, and generating a compound IV under the action of a reducing agent; and removing benzyl from the compound IV under the action of a catalyst/hydrogen to generate a compound I. 本发明公开了一种2-氨基-2-(1-甲基-4-哌啶基)乙醇的制备方法，包括以下步骤：将2-甲基-2-丙烷基-4-(1-氨基-2-甲氧基-2-氧代乙基)-1-哌啶羧酸酯(化合物II)在碱1作用下与溴化苄反应生成化合物III；化合物III溶于有机溶剂中，在还原剂作用下生成化合物IV；化合物IV在催化剂/氢气作用下，脱除苄基生成化合物I。