Cell classification result correction method based on multi-peak fitting analysis

The invention discloses a cell classification result correction method based on multi-peak fitting analysis, and the method comprises the following steps: classifying various cells by using an automatic classification algorithm according to sample cell characteristics collected by a cell analyzer; a...

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Bibliographische Detailangaben
Hauptverfasser: WANG MENGLONG, WEI XIAO, QIN XINLONG
Format: Patent
Sprache:chi ; eng
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Zusammenfassung:The invention discloses a cell classification result correction method based on multi-peak fitting analysis, and the method comprises the following steps: classifying various cells by using an automatic classification algorithm according to sample cell characteristics collected by a cell analyzer; according to an automatic classification result, extracting a feature histogram of overlapped cell classification, and extracting a noise signal obtained by Gaussian filtering elimination sampling with a step length of 3 or 5 in the process; estimating Gaussian distribution parameters according to the cell distribution, and respectively executing coarse Gaussian distribution fitting on each wave crest; on the basis of the rough fitting result, executing overlapped Gaussian distribution fitting, and obtaining the distribution parameters of cell peaks; selecting an overlapping region of each cell peak, calculating the area ratio of the overlapping region, completing cell content correction, and improving the classific