Refining method of avibactam sodium intermediate and avibactam sodium intermediate prepared thereby

The invention relates to a refining method of an avibactam sodium intermediate as shown in a formula 2, which comprises the following steps: S10, providing an avibactam sodium intermediate crude product, mixing the avibactam sodium intermediate crude product with a solvent, heating and dissolving to obtain a solution a, wherein the solvent comprises a solvent A, and the solvent A is a good solvent of the avibactam sodium intermediate and is an alcohol organic matter; and S20, adding methyl tert-butyl ether into the solution a while the solution is hot, and cooling to crystallize. The invention also relates to the avibactam sodium intermediate prepared by the refining method of the avibactam sodium intermediate. 本发明涉及一种式2所示阿维巴坦钠中间体的精制方法，包括以下步骤：S10，提供阿维巴坦钠中间体粗品，将所述阿维巴坦钠中间体粗品与溶剂混合并加热溶解得到溶液a，所述溶剂包括溶剂A，所述溶剂A为所述阿维巴坦钠中间体的良溶剂且所述溶剂A为醇类有机物；以及S20，趁热向所述溶液a中加入甲基叔丁基醚，降温析晶。本发明还涉及一种由所述阿维巴坦钠中间体的精制方法制备得到的阿维巴坦钠中间体。