Preparation method of crystal form B avibactam sodium

The invention discloses a preparation method of crystal form B avibactam sodium, which comprises the following steps: S100, adding methanol and water into avibactam sodium, stirring, heating and dissolving to obtain an avibactam sodium solution; and S200, adding an alcohol poor solvent into the avibactam sodium solution, cooling to a first temperature, stirring for growing crystals, and then continuously cooling to a second temperature for devitrification. 本发明公开了一种晶型B阿维巴坦钠的制备方法，包括：S100，向阿维巴坦钠中加入甲醇和水，然后搅拌并加热溶解得到阿维巴坦钠溶液；S200，向所述阿维巴坦钠溶液中加入醇类不良溶剂，降温至第一温度后进行搅拌养晶，然后继续降温至第二温度进行析晶。